RNAInterference相关论文
目的:探讨PAX2基因沉默对梗阻性肾病大鼠肾功能的影响。方法:64只幼年雄性大鼠随机分为阴性对照组(NC)和沉默组(RNAi)各32只，均于转......
Integrated transcriptome sequencing and RNA interference reveals molecular changes in Diaphorina cit
Validamycin has been widely used as a specific competitive inhibitor of tre-halase.In our previous research,validamycin ......
A dsRNA-degrading nuclease (dsRNase2)limits RNAi efficiency in the Asian corn borer (Ostrinia furnac
The efficiency of RNA interference (RNAi) varies substantially among dif-ferent insect species.Rapid degradation of doub......
Soybean (Glycine max (L.) Merr.), a typical short-day plant, is sensitive to photoperiod, which limits the geographical ......
Brain-Derived Glia Maturation Factor β Participates in Lung Injury Induced by Acute Cerebral Ischemi
Brain damage can cause lung injury.To explore the mechanism underlying the lung injury induced by acute cerebral ischemi......
Downregulation of the nucleosome-binding protein 1(NSBP1)gene can inhibit the in vitro and in vivo p
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Preliminary experimental study of urethral reconstruction with tissue engineering and RNA interferen
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Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon ca
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Schistosomes infect around 280 million people worldwide.The worms survive in the veins of the final host,where thioredox......
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Traceable nanoparticle with temporally release ability to control neural stem cell differentiation f
Alzheimers disease (AD) is the most prevalent age-related neurodegenerative disorder.The predominant pathologies of AD a......
RNA interference(RNAi)is emerging as one of promising strategies for tumor therapy,especially for inhibiting tumor metas......
Silencing of molt-regulating transcription factor gene, CiHR3 affects growth and development of suga
RNA interference (RNAi) is a technology for conducting functional genomic studies and a potential tool for crop protecti......
Vitellogenin (Vg) is the precursor of yolk protein,which functions as a nutritive resource that is important for embryon......
Molecular Cloning, Expression and Oxidative Stress Response of the Vitellogenin Gene (AccVg) from Ap
Vitellogenin (Vg) is a yolk precursor protein in most oviparous females.However,Vg has not been studied in the Apis cera......
Transcriptome response of Aedes aegypti against Bacillus thuringiensis and the pathway for enhance t
It has been estimated that over one million people worldwide die from mosquito transmitted diseases every year.Control o......
Arginine kinase(AK)is a potential target of RNA interference(RNAi)for pest control due to its unique phosphotransferase ......
Molecular Characterization and RNA Interference of Midgut Aminopeptidase N Isozymes from Chilo suppr
Genetically modified rice expressing cry genes from Bacillus thuringiensis (Bt) has exhibited high efficiency and can pr......
Molecular characterization and functional analysis of a new acid phosphatase gene (Ha-acp1) from Het
For sedentary endo-parasitic nematodes, parasitism genes encoding secretory protein expressed in the subventral glands c......
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Distribution of lethal giant larvae (Lgl) protein in the tegument and negative impact of siRNA:based
Lethal giant larvae (Lgl) is evolutionarily conserved tumor suppressor present in fungi and animals.It plays an essentia......
Objectives: We introduced an adenoviral vector expressing interleukin-1b (IL-1b) small hairpin RNA (shRNA) into the inju......
Efficient and non-Toxic Biological response carrier Delivering TNF-α shRNA for gene silencing in a M
Small interfering RNA (siRNA) is an effective and specific method for silencing genes. However, an efficient and nontoxi......
MicroRNA-1275 inhibits cell migration and invasion in gastric cancer by regulating vimentin and E-ca
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Objective Pancreatic cancer(PCa)is the most lethal solid tumour and is the fourth leading cause of cancer-related death,......
Comparative Proteomics in gastric cancer cell line BGC823 after ZNF139 gene inhibited with RNA inter
Objective: To study changes of proteins after zinc finger protein 139 (ZNF 139) gene was inhibited in gastric cancer cel......
Emerging evidence indicates that dysregulated long non-coding RNA (lncRNA) HOTAIR correlates highly with tumor invasion ......
The chemotherapy of glioma is usually failure due to the multidrug resistance.The authors investigated the reversal effe......
Effects of CXCR4 gene silencing by lentivirus shRNA on metastatic characteristics of the EC9706 huma
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Background: RNA interference(RNAi)as a posttranscriptional gene-silencing mechanism triggered by double-stranded RNA(dsR......
Background: B7-H3, a member from B7-family co-stimulatory ligands, plays an important role in adaptive immune responses....
Attenuation of NK Cell-mediated Liver Injury Through Genetically Manipulating IL-10, CCL5 and CX3CL1
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Triterpenes in Betula Platyphlla suk.have vital activities of anti-HIV and anti-tumor,and the active components of white......
Influence of cyclinD1 targeting on cell proliferation and related signal transduction pathway in kel
To investigate the effect of sequence-specific small interfering RNA (siRNA)on suppressing cyclinD 1 expression and prol......
RNAi-mediated silencing of transcription factor SoxE gene expression in the silkworm ovary-derived B
Transcription factor SoxE is mainly expressed in gonad and involved in the regulation of gonad development and sex deter......
Trehalase(TRE)is an enzyme that hydrolyzes trehalose to yield two glucose molecules and it is divided into two types,sol......
Silencing COI1 in jasmonate (JA) pathway increases rice susceptibility to chewing insects and impair
The jasmonate (JA) pathway plays a key role in plant defense responses against herbivorous insects.CORONATINE INSENSITIV......
Functional Analysis of the Isopentenyl Diphosphate Isomerase of Salvia miltiorrhiza via Color Comple
Isopentenyl diphosphate isomerase (IPI)catalyzes the isomerism between the common precursor of terpene substances isopen......
RNA interference-mediated phosphodiesterase-4D knockdown in the prefrontal cortex elicits antidepres
OBJECTIVE Phosphodiesterase 4 (PDE4), specific for cyclic AMP (cAMP)-hydrolyzing, has four isoforms (PDE4A-D) with at le......
Adeno-Associated Virus 2/1-Based RNA Interference:Ablation of Phospholamban Improve Cardiac Function
Objective:to investigate the efficacy of the RNAi method for ablation of PLB gene expression and improvement SERCA2a act......
The effects of inhibiting RhoA by Stealth RNA on high glucose-induced RhoA/ROCK signaling pathway in
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谷氧还蛋白(Glutaredoxins,Grxs),又叫巯基转移酶(thioltransferase,TTase),在植物和哺乳动物中能够维持细胞内的氧化还原平衡和保......
Off-target effects are one of the most serious problems in RNA interference(RNAi)....
Effect of Diflubenzuron and RNA Interference in Chitin Synthase Encoding Gene in Brown Citrus Aphids
As one of the most crucial components in the cuticle,cuticular lining of the foregut,hindgut,trachea,and peritrophic mem......
